Cladribine
Cladribine (2CdA) is a purine nucleoside analog that acts as an adenosine deaminase inhibitor, used in research on lymphoproliferative disorders. It is applied in both in vitro and in vivo studies to investigate its cytotoxic mechanisms against malignant lymphocytes, such as in hairy cell leukemia.
Product Specifications
CAS Number
4291-63-8
Product Name Alternative
DLBCL, CLL, CldAdo, cell, Cladribine, chronic, Adenosinedeaminase, Adenosine Deaminase, Adenosine deaminase, Adenosine deaminase (MM1.S cells), Adenosine deaminase (RPMI8226 cells), Adenosine deaminase (U266 cells), 2-chlorodeoxyadenosine, 2CdA, 2-Chloro-2′-deoxyadenosine, Apoptosis, mucosa-associated, multiple, inhibit, lymphocytic, lymphoid, lymphoma, hairy, follicular, MCL, mantle, MALT, leukemia, HCL, Inhibitor, tissue, sclerosis
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.00% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:255 mg/mL (892.58 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (17.5 mM)
Smiles
Nc1nc (Cl) nc2n (cnc12) [C@H]1C[C@H] (O) [C@@H] (CO) O1
Molecular Formula
C10H12ClN5O3
Molecular Weight
285.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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