Dienogest

Dienogest (STS 557) is a fourth-generation, non-ethinylated progestin with oral activity, exhibiting antiproliferative, antiandrogenic, anti-inflammatory, and antiangiogenic properties. It is utilized in hormone therapy and contraception, and is widely applied in preclinical research for studying endometriosis and related gynecological disorders in both in vitro and in vivo models.

Product Specifications

CAS Number

65928-58-7

Product Name Alternative

Inhibitor, EstrogenReceptor, Estrogen Receptor, endometriosis, EM-PR cells, ER, menopause, menorrhagia, NR3C3, inhibit, COX-2, Dienogest, Apoptosis, Autophagy, STS 557, STS557, STS-557, ProgesteroneReceptor, Progesterone Receptor, progestogen Receptor, progestogenReceptor, PGE2

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

DMSO:60 mg/mL (192.67 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.42 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)