Cilastatin
Cilastatin is a dehydropeptidase-I inhibitor co-administered with the antibiotic imipenem to prevent its renal degradation, thereby enhancing therapeutic efficacy. It also inhibits leukotriene D4 metabolism and is used in research involving bacterial infection models and studies of leukotriene-mediated inflammatory pathways.
Product Specifications
CAS Number
82009-34-5
Product Name Alternative
Inhibitor, inhibit, MK0791, MK-0791, MK 0791, metallob-lactamase, Cilastatin, CphA, dehydropeptidase, Dipeptidase 1, adjunct, Bacterial, Antibiotic, antibacterial, peptidase, zinc, Renal
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
97.76% (May vary between batches)
Solubility
DMSO:45 mg/mL (125.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.58 mM)
Smiles
CC1 (C) C[C@@H]1C (=O) N\C (=C/CCCCSC[C@H] (N) C (O) =O) C (O) =O
Molecular Formula
C16H26N2O5S
Molecular Weight
358.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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