Bax (Apoptosis Marker) Mouse Monoclonal Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

[BAX]

NCBI Gene ID

581

Reactivity

Human, Monkey.<br>Does not react with Mouse and Rat

Storage Conditions

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Other Gene Names

[BAX; BAX; BCL2L4; BCL2L4; Bcl2-L-4]

Short Name

[Bax]

Other Product Names

[apoptosis regulator BAX isoform 1; Apoptosis regulator BAX; apoptosis regulator BAX; BCL2 associated X, apoptosis regulator; Bcl-2-like protein 4; Bcl2-L-4]