What is the catalog number for Ivacaftor?

The catalog number for Ivacaftor is orb1305294.

What sizes are available for Ivacaftor?

Ivacaftor is available in the following size(s): 1 mg, 2 mg, 5 mg, 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does Ivacaftor come in?

Ivacaftor is available in 9 different pack sizes.

Is Ivacaftor in stock?

Ivacaftor is currently made to order / not held in immediate stock. Contact us for lead time.

Ivacaftor

Ivacaftor (VX-770) is a CFTR potentiator effective on G551D and F508del mutants, with EC50 values of 100 nM and 25 nM, respectively, in Fisher rat thyroid cell assays. It is a key research tool for studying CFTR channel function and rescue in cellular models of cystic fibrosis, supporting both in vitro and preclinical in vivo research.

Product Specifications

CAS Number

873054-44-5

Product Name Alternative

Inhibit, Ivacaftor, Ivacaftor (VX-770), G551D-CFTR, F508del-CFTR, Inhibitor, Autophagy, Cystic fibrosis transmembrane conductance regulator, CFTR, VX770, VX-770, VX 770

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:252 mg/mL (642.05 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.74 mM)