MUC18/ CD146
Product Specifications
Gene Name
[MCAM]
NCBI Gene ID
4162
Reactivity
Human.
Storage Conditions
Store at 2 to 8 °C. Antibody is stable for 24 months.
Specificity
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Other Gene Names
[MCAM; MCAM; CD146; MUC18; MUC18]
Short Name
[MUC18]
Other Product Names
[cell surface glycoprotein MUC18; Cell surface glycoprotein MUC18; cell surface glycoprotein MUC18; melanoma cell adhesion molecule; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD_antigen: CD146]
NCBI Accession Number
NP_006491.2
Uniprot Accession Number
P43121
Available Sizes
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