Vidofludimus
Vidofludimus (SC12267) is a potent and selective small molecule inhibitor of dihydroorotate dehydrogenase (DHODH) . It has demonstrated efficacy in preclinical models of autoimmune diseases, such as multiple sclerosis and lupus, through both in vitro enzymatic assays and in vivo studies.
Product Specifications
CAS Number
717824-30-1
Product Name Alternative
RNA Synthesis, RNASynthesis, SC 12267, SC12267, SC-12267, Vidofludimus, 4sc-101, DHODH, Dihydroorotate Dehydrogenase, DNASynthesis, DNA/RNA Synthesis, DNA Synthesis, dihydroorotate dehydrogenase (DHODH), Inhibitor, Interleukin Related, Interleukin, farnesoid X receptor (FXR), fatty liver, Human DHODH, FXR, immunomodulatory, inflammatory bowel disease (IBD), NR1H4, inhibit, non-alcoholic fatty liver disease (NAFLD), oral
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology
Purity
98.33% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+90% Corn Oil:3.3 mg/mL (9.29 mM) ; DMSO:100 mg/mL (281.4 mM) ; Ethanol:1 mg/mL (2.81 mM)
Smiles
COc1cccc (c1) -c1ccc (NC (=O) C2=C (CCC2) C (O) =O) c (F) c1
Molecular Formula
C20H18FNO4
Molecular Weight
355.36
Storage Conditions
-20°C
Notes
For research use only.
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