Fostamatinib Disodium
Fostamatinib Disodium (R788 Disodium) is an orally bioavailable inhibitor of spleen tyrosine kinase (Syk) . It is used in research to investigate immunomodulation and inflammation, with applications in both in vitro cellular assays and in vivo models of autoimmune and hematologic disorders.
Product Specifications
CAS Number
1025687-58-4
Product Name Alternative
CD135, Cluster of differentiation antigen 135, Inhibitor, Fostamatinib, Fostamatinib Disodium, Fms like tyrosine kinase 3, FLT3, inhibit, Tamatinib Fosdium, Syk, Spleen tyrosine kinase, R 788, R788 (Fostamatinib), R788 (Fostamatinib) Disodium, R788 Disodium, R788 (Disodium), R788, R-788
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
96.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.2 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:50 mg/mL (80.07 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
[Na+].[Na+].COc1cc (Nc2ncc (F) c (Nc3ccc4OC (C) (C) C (=O) N (COP ([O-]) ([O-]) =O) c4n3) n2) cc (OC) c1OC
Molecular Formula
C23H24FN6O9P·2Na
Molecular Weight
624.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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