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KN-93 Phosphate

KN-93 (Phosphate) is a potent and selective CaMKII inhibitor (Ki=370 nM) that acts by competitively disrupting calmodulin binding. It is widely used in cardiovascular and neuroscience research to study calcium signaling pathways and has been shown to inhibit hepatic stellate cell proliferation in vitro.

Product Specifications

CAS Number

1913269-12-1

Product Name Alternative

CaMKII, KN93 Phosphate, KN-93 Phosphate, KN 93 Phosphate

Field of Research

Cell Biology, Neuroscience

Purity

99.58% (May vary between batches)

Solubility

PBS:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:100 mg/mL (166.94 mM) ; DMSO:135 mg/mL (225.36 mM) ; Saline:< 1 mg/mL (insoluble or slightly soluble)

Smiles

OP (O) (O) =O.COc1ccc (cc1) S (=O) (=O) N (CCO) c1ccccc1CN (C) C\C=C\c1ccc (Cl) cc1

Molecular Formula

C26H32ClN2O8PS

Molecular Weight

599.03

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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