CHIR-98014
CHIR-98014 is a potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor. It enhances insulin-stimulated glucose uptake and metabolism in both cellular and animal models, making it a valuable research tool for studying diabetes, insulin resistance, and Wnt/β-catenin signaling pathways.
Product Specifications
CAS Number
252935-94-7
Product Name Alternative
BFGFR, CT98014, CT 98014, c-Src, CT-98014, CHIR 98014, CHIR-98014, CHIR98014, p70 S6K, inhibit, Inhibitor, Glycogen synthase kinase 3, Glycogen synthase kinase-3, GSK-3β, GSK-3α, GSK3, GSK-3, S6 Kinase, S6Kinase
Field of Research
Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.09% (May vary between batches)
Solubility
DMSO:4.87 mg/mL (10.01 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
ClC1=C (C=2C (=CN=C (NCCNC=3N=C (N) C (N (=O) =O) =CC3) N2) N4C=CN=C4) C=CC (Cl) =C1
Molecular Formula
C20H17Cl2N9O2
Molecular Weight
486.31
Storage Conditions
-20°C
Notes
For research use only.
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