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CHIR-98014

CHIR-98014 is a potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor. It enhances insulin-stimulated glucose uptake and metabolism in both cellular and animal models, making it a valuable research tool for studying diabetes, insulin resistance, and Wnt/β-catenin signaling pathways.

Product Specifications

CAS Number

252935-94-7

Product Name Alternative

BFGFR, CT98014, CT 98014, c-Src, CT-98014, CHIR 98014, CHIR-98014, CHIR98014, p70 S6K, inhibit, Inhibitor, Glycogen synthase kinase 3, Glycogen synthase kinase-3, GSK-3β, GSK-3α, GSK3, GSK-3, S6 Kinase, S6Kinase

Field of Research

Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

97.09% (May vary between batches)

Solubility

DMSO:4.87 mg/mL (10.01 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

ClC1=C (C=2C (=CN=C (NCCNC=3N=C (N) C (N (=O) =O) =CC3) N2) N4C=CN=C4) C=CC (Cl) =C1

Molecular Formula

C20H17Cl2N9O2

Molecular Weight

486.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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