Masitinib
Masitinib (AB1010) is a tyrosine kinase inhibitor used in veterinary medicine to treat canine mast cell tumors, marketed as Masivet in Europe and Kinavet in the USA. Its research applications extend to investigating mast cell-related diseases and kinase signaling pathways in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
790299-79-5
Product Name Alternative
C-Kit, cKit, CD117, AB-1010, AB1010, AB 1010, Abl1, Apoptosis, BcrAbl, cFms, c-Fms, Masitinib, Inhibitor, Hck, FAK, FGFR, Focal adhesion kinase, Fibroblast growth factor receptor, inhibit, Lyn B, Kit, PDGFRβ, PDGFRα, PDGFR, Platelet-derived growth factor receptor, PTK2, PTK2 protein tyrosine kinase 2, SCFR, Src
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
97.56% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:250 mg/mL (501.36 mM) ; Ethanol:4 mg/mL (8.02 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.01 mM)
Smiles
N (C1=NC (=CS1) C=2C=CC=NC2) C3=CC (NC (=O) C4=CC=C (CN5CCN (C) CC5) C=C4) =CC=C3C
Molecular Formula
C28H30N6OS
Molecular Weight
498.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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