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Masitinib

Masitinib (AB1010) is a tyrosine kinase inhibitor used in veterinary medicine to treat canine mast cell tumors, marketed as Masivet in Europe and Kinavet in the USA. Its research applications extend to investigating mast cell-related diseases and kinase signaling pathways in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

790299-79-5

Product Name Alternative

C-Kit, cKit, CD117, AB-1010, AB1010, AB 1010, Abl1, Apoptosis, BcrAbl, cFms, c-Fms, Masitinib, Inhibitor, Hck, FAK, FGFR, Focal adhesion kinase, Fibroblast growth factor receptor, inhibit, Lyn B, Kit, PDGFRβ, PDGFRα, PDGFR, Platelet-derived growth factor receptor, PTK2, PTK2 protein tyrosine kinase 2, SCFR, Src

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Purity

97.56% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:250 mg/mL (501.36 mM) ; Ethanol:4 mg/mL (8.02 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.01 mM)

Smiles

N (C1=NC (=CS1) C=2C=CC=NC2) C3=CC (NC (=O) C4=CC=C (CN5CCN (C) CC5) C=C4) =CC=C3C

Molecular Formula

C28H30N6OS

Molecular Weight

498.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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