Almorexant
Almorexant (ACT 078573) is a potent dual antagonist of orexin receptors OX1 (Ki=1.3 nM) and OX2 (Ki=0.17 nM) . It is a valuable research tool for investigating sleep-wake regulation and has been utilized in both in vitro binding assays and in vivo models of insomnia.
Product Specifications
CAS Number
871224-64-5
Product Name Alternative
OXReceptor, Cataplexy, Caspase, ACT078573, ACT-078573, ACT 078573, Almorexant, Ca channels, Ca2+ channels, Calcium Channel, Apoptosis, AsPC-1 cells, GPCR, hypocretin, Hypocretin Receptor, HCRT Receptor, HPAF-II cells, Inhibitor, inhibit, orexin, Orexin Receptor (OX Receptor), OX2, OX Receptor, OX1, narcolepsy, pancreatic cancer, Pancreatic ductal adenocarcinoma, PDAC
Field of Research
Cell Biology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
95.59% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.9 mM) ; DMSO:45 mg/mL (87.79 mM)
Smiles
C (CC1=CC=C (C (F) (F) F) C=C1) [C@H]2C=3C (=CC (OC) =C (OC) C3) CCN2[C@@H] (C (NC) =O) C4=CC=CC=C4
Molecular Formula
C29H31F3N2O3
Molecular Weight
512.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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