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MyoD1 (Rhabdomyosarcoma Marker) Mouse Monoclonal Antibody

Product Specifications

Gene Name

[MYOD1]

NCBI Gene ID

4654

Reactivity

Human, Mouse, Rat, Chicken

Storage Conditions

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Recognizes a phosphor-protein of 45kDa, identified as MyoD1. The epitope of this MAb maps between amino acid 180-189 in the C-terminal of mouse MyoD1 protein. It does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilms tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing's sarcomas and alveolar soft part sarcomas.

Other Gene Names

[MYOD1; MYOD1; PUM; MYF3; MYOD; bHLHc1; BHLHC1; MYF3; MYOD; bHLHc1; Myf-3]

Short Name

[MyoD1]

Other Product Names

[myoblast determination protein 1; Myoblast determination protein 1; myoblast determination protein 1; myogenic differentiation 1; Class C basic helix-loop-helix protein 1; bHLHc1; Myogenic factor 3; Myf-3]

NCBI GI Number

23111009

NCBI Accession Number

NP_002469.2

NCBI GB Accession Number

NM_002478.4

Uniprot Accession Number

P15172

CAS Number

9007-83-4

Available Sizes

Curated Selection

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