G-749
G-749 is a novel, potent small-molecule FLT3 inhibitor effective against both wild-type and mutant FLT3 kinases. It demonstrates sustained inhibitory activity, making it a valuable research tool for investigating acute myeloid leukemia (AML) in both cellular and animal models.
Product Specifications
CAS Number
1457983-28-6
Product Name Alternative
CRET, Denfivontinib, drug, Cluster of differentiation antigen 135, CD135, acute, Apoptosis, AML, Aurora Kinase, AuroraKinase, Aurora B, inhibit, kinase, myeloid, Mer, Fms-like, Fms like tyrosine kinase 3, FLT3, FLT3 (D835Y), G 749, G749, G-749, Inhibitor, leukemia, tyrosine, TAMReceptor, TAM Receptor, resistance, RET, receptor
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
98.32% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CN1CCC (CC1) Nc1nc (Nc2ccc (Oc3ccccc3) cc2) c2c (n1) c (Br) c[nH]c2=O
Molecular Formula
C25H25BrN6O2
Molecular Weight
521.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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