MK-0752
MK-0752 is a potent γ-secretase inhibitor with an IC50 of 5 nM for reducing Aβ40 production. This small molecule is used in research to study Alzheimer's disease pathology, enabling in vitro and in vivo investigations of amyloid-beta modulation.
Product Specifications
CAS Number
471905-41-6
Product Name Alternative
Gamma secretase, Gammasecretase, Inhibitor, MK 0752, MK0752, MK-0752, inhibit, blood-brain, bAmyloid, barrier, b Amyloid, Aβ40, Aβ, Beta Amyloid, BetaAmyloid, CNS, γ-secretase, β Amyloid, βAmyloid
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
DMSO:89 mg/mL (200.95 mM) ; Ethanol:45 mg/mL (101.6 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.45 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
OC (=O) CC[C@H]1CC[C@@] (CC1) (c1cc (F) ccc1F) S (=O) (=O) c1ccc (Cl) cc1
Molecular Formula
C21H21ClF2O4S
Molecular Weight
442.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
M2424-HRP 100 µL
Matrix Metalloproteinase 8 (MMP-8, Neutrophil ProCollagenase, Collagenase2) (HRP) discontinued
Sign In for Pricing
View Details 
27893091 4x 500 ng
MADCAM1-set siRNA/shRNA/RNAi Lentivector (Human)
Sign In for Pricing
View Details