MALT1 (MALT-Lymphoma Marker) Mouse Monoclonal Antibody
Product Specifications
Gene Name
[MALT1]
NCBI Gene ID
10892
Reactivity
Human
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
Other Gene Names
[MALT1; MALT1; MLT; MLT1; IMD12; PCASP1; MLT]
Short Name
[MALT1 (MALT-Lymphoma Marker)]
Other Product Names
[mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform a; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; MALT1 paracaspase; MALT lymphoma-associated translocation; Paracaspase]
NCBI GI Number
5803078
NCBI Accession Number
NP_006776.1
NCBI GB Accession Number
NM_006785.3
Uniprot Accession Number
Q9UDY8
CAS Number
9007-83-4
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
