Triparanol
Triparanol (NSC-65345) is a research compound that inhibits Hedgehog signaling by disrupting the post-translational modification of its ligands and the sterol-sensing domain of PTCH1. It has demonstrated antitumor activity in human models and functions as an antilipemic agent, though it is noted for significant ocular toxicity.
Product Specifications
CAS Number
78-41-1
Product Name Alternative
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
99.72% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.28 mM) ; DMSO:50 mg/mL (114.16 mM)
Smiles
C (CC1=CC=C (Cl) C=C1) (O) (C2=CC=C (OCCN (CC) CC) C=C2) C3=CC=C (C) C=C3
Molecular Formula
C27H32ClNO2
Molecular Weight
438
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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