c-Myb Oncoprotein
Product Specifications
Gene Name
[MYB]
NCBI Gene ID
4602
Reactivity
Human.
Storage Conditions
Store at 2 to 8 °C. Antibody is stable for 24 months.
Specificity
The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular hom- olog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-ter- minal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
Other Gene Names
[MYB; MYB; efg; Cmyb; c-myb; c-myb_CDS]
Short Name
[c-Myb Oncoprotein]
Other Product Names
[transcriptional activator Myb isoform 3; Transcriptional activator Myb; transcriptional activator Myb; c-myb8B_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; proto-oncogene c-Myb; c-myb protein (140 AA); v-myb avian myeloblastosis viral oncogene homolog; Proto-oncogene c-Myb]
NCBI GI Number
194328727
NCBI Accession Number
NP_001123644.1
NCBI GB Accession Number
NM_001130172.1
Uniprot Accession Number
P10242
Available Sizes
Curated Selection
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