Almotriptan
Almotriptan (LAS 31416) is a selective 5-HT1B/1D receptor agonist used as a triptan medication for migraine. Its mechanism involves cranial vasoconstriction, which redistributes blood flow by increasing cerebral circulation while reducing extracerebral vessel flow. This pharmacological action has been characterized in both in vitro binding assays and in vivo models of migraine.
Product Specifications
CAS Number
154323-57-6
Product Name Alternative
5HT Receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, Almotriptan, 5-HT Receptor, 5-HT1B/1D, LAS 31416, LAS31416, LAS-31416, Inhibitor, inhibit, Serotonin Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.85% (May vary between batches)
Solubility
DMSO:65 mg/mL (193.76 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.96 mM)
Smiles
CN (C) CCc1c[nH]c2ccc (CS (=O) (=O) N3CCCC3) cc12
Molecular Formula
C17H25N3O2S
Molecular Weight
335.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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