Eosinophil Peroxidase
Product Specifications
Gene Name
[EPX]
NCBI Gene ID
8288
Reactivity
Human.
Storage Conditions
Antibody without azide - store at -20 to -80°C.<br>Non-hazardous. No MSDS required.
Specificity
Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).
Other Gene Names
[EPX; EPX; EPO; EPP; EPX-PEN; EPER; EPO; EPP; EPO]
Short Name
[Eosinophil Peroxidase]
Other Product Names
[eosinophil peroxidase preproprotein; Eosinophil peroxidase; eosinophil peroxidase; eosinophil peroxidase]
NCBI GI Number
4503595
NCBI Accession Number
NP_000493.1
NCBI GB Accession Number
NM_000502.4
Uniprot Accession Number
P11678
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
