SBI-0206965
SBI-0206965 is a selective, cell-permeable inhibitor of the autophagy-initiating kinase ULK1, with an IC50 of 108 nM, and also inhibits ULK2 (IC50 = 711 nM) . This tool compound is widely used in vitro and in vivo to investigate the fundamental role of autophagy in cancer, neurodegenerative diseases, and metabolic disorders.
Product Specifications
CAS Number
1884220-36-3
Product Name Alternative
Unc-51 like kinase, ULK1, ULK, SBI 0206965, SBI0206965, SBI-0206965, Apoptosis, Autophagy, inhibit, Inhibitor
Field of Research
Cell Biology
Purity
>98%
Bioactivity
ULK1 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml)
Smiles
CNC (=O) c1ccccc1Oc1nc (Nc2cc (OC) c (OC) c (OC) c2) ncc1Br
Molecular Formula
C21H21BrN4O5
Molecular Weight
489.32
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2- ((5-Bromo-2- ((3,4,5-trimethoxyphenyl) amino) pyrimidin-4-yl) oxy) -N-methylbenzamide
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