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Fibronectin

Product Specifications

Gene Name

[FN1]

NCBI Gene ID

2335

Reactivity

Human, Pig, Mouse and Rat. Others-not known.

Storage Conditions

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Fibronectin is a soluble dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.

Other Gene Names

[FN1; FN1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; FN; FN; CIG]

Short Name

[Fibronectin]

Other Product Names

[fibronectin isoform 3 preproprotein; Fibronectin; fibronectin; cold-insoluble globulin; migration-stimulating factor; fibronectin 1; Cold-insoluble globulin; CIG]

NCBI GI Number

16933542

NCBI Accession Number

NP_002017.1

NCBI GB Accession Number

NM_002026.2

Uniprot Accession Number

P02751

Available Sizes

Frequently Asked Questions

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