Polmacoxib
Polmacoxib (CG 100649) is a novel dual carbonic anhydrase and COX-2 inhibitor. It has demonstrated efficacy in suppressing premalignant and malignant colorectal lesions in mouse models, partly by inhibiting tumor cell proliferation, highlighting its research utility in oncology and inflammation studies.
Product Specifications
CAS Number
301692-76-2
Product Name Alternative
Cyclooxygenase, COX-2, CG100649, CG-100649, CG 100649, colorectal, COX, Carbonate dehydratase, Carbonic Anhydrase, carbonic anhydrase, CarbonicAnhydrase, adenoma, inflammatory, NSAID, inhibit, Inhibitor, tumor, polyp, Polmacoxib, orthotopic
Field of Research
Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
97.88% (May vary between batches)
Solubility
H2O:Insoluble; DMSO:55 mg/mL (152.19 mM)
Smiles
CC1 (C) OC (=C (C1=O) c1cccc (F) c1) c1ccc (cc1) S (N) (=O) =O
Molecular Formula
C18H16FNO4S
Molecular Weight
361.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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