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Polmacoxib

Polmacoxib (CG 100649) is a novel dual carbonic anhydrase and COX-2 inhibitor. It has demonstrated efficacy in suppressing premalignant and malignant colorectal lesions in mouse models, partly by inhibiting tumor cell proliferation, highlighting its research utility in oncology and inflammation studies.

Product Specifications

CAS Number

301692-76-2

Product Name Alternative

Cyclooxygenase, COX-2, CG100649, CG-100649, CG 100649, colorectal, COX, Carbonate dehydratase, Carbonic Anhydrase, carbonic anhydrase, CarbonicAnhydrase, adenoma, inflammatory, NSAID, inhibit, Inhibitor, tumor, polyp, Polmacoxib, orthotopic

Field of Research

Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

97.88% (May vary between batches)

Solubility

H2O:Insoluble; DMSO:55 mg/mL (152.19 mM)

Smiles

CC1 (C) OC (=C (C1=O) c1cccc (F) c1) c1ccc (cc1) S (N) (=O) =O

Molecular Formula

C18H16FNO4S

Molecular Weight

361.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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