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Zoledronic acid monohydrate

Zoledronic acid monohydrate (CGP 42446) is a synthetic bisphosphonate that potently inhibits osteoclast-mediated bone resorption. It is widely used in research models of osteoporosis, bone metastasis, and hypercalcemia, with applications in both in vitro cellular assays and in vivo animal studies.

Product Specifications

CAS Number

165800-06-6

Product Name Alternative

Inhibit, Inhibitor, CGP42446, CGP-42446, CGP42446A, CGP 42446, bisphosphonate, anti-cancer, anti-resorptive, Apoptosis, Autophagy, activity, osteoclast, osteoporosis, ZOL 446, ZOL446, ZOL-446, Zoledronic acid, Zoledronic acid Hydrate, Zoledronic acid hydrate, Zoledronic acid monohydrate, Zoledronic acid Monohydrate, zoledronate

Field of Research

Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery

Purity

≥95% (May vary between batches)

Solubility

0.1M NaOH:10 mg/mL (34.47 mM) ; H2O:Insoluble; DMSO:< 1 mg/mL (insoluble or slightly soluble)

Smiles

OC (P (O) (O) =O) (P (O) (O) =O) CN1C=CN=C1.[H]O[H]

Molecular Formula

C5H12N2O8P2

Molecular Weight

290.1

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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