SAR-020106
SAR-020106 is a selective, ATP-competitive small molecule inhibitor of CHK1, demonstrating potent activity with an IC50 of 13.3 nM. It is a valuable research tool for studying DNA damage response pathways and has been utilized in both in vitro and in vivo models of oncology research.
Product Specifications
CAS Number
1184843-57-9
Product Name Alternative
Cycle, cells, colon, Checkpoint Kinase (Chk), CHK1, cancer, arrest, antitumor, inhibit, Inhibitor, selectivity, SAR 020106, SAR020106, SAR-020106, SN38, SW620
Field of Research
Cell Biology
Purity
95.11% (May vary between batches)
Solubility
DMSO:12 mg/mL (31.34 mM)
Smiles
C[C@H] (CN (C) C) Oc1nc (Nc2cc3cccc (Cl) c3cn2) cnc1C#N
Molecular Formula
C19H19ClN6O
Molecular Weight
382.85
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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