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SAR-020106

SAR-020106 is a selective, ATP-competitive small molecule inhibitor of CHK1, demonstrating potent activity with an IC50 of 13.3 nM. It is a valuable research tool for studying DNA damage response pathways and has been utilized in both in vitro and in vivo models of oncology research.

Product Specifications

CAS Number

1184843-57-9

Product Name Alternative

Cycle, cells, colon, Checkpoint Kinase (Chk), CHK1, cancer, arrest, antitumor, inhibit, Inhibitor, selectivity, SAR 020106, SAR020106, SAR-020106, SN38, SW620

Field of Research

Cell Biology

Purity

95.11% (May vary between batches)

Solubility

DMSO:12 mg/mL (31.34 mM)

Smiles

C[C@H] (CN (C) C) Oc1nc (Nc2cc3cccc (Cl) c3cn2) cnc1C#N

Molecular Formula

C19H19ClN6O

Molecular Weight

382.85

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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