Lurasidone
Lurasidone (SM-13496) is a small molecule acting as a dopamine D2 and 5-HT7 receptor antagonist, with respective IC50 values of 1.68 nM and 0.495 nM, and as a 5-HT1A receptor partial agonist (IC50=6.75 nM) . It is widely used in preclinical research for studying schizophrenia and mood disorders, employing both in vitro binding assays and in vivo behavioral models.
Product Specifications
CAS Number
367514-87-2
Product Name Alternative
5-HT Receptor, 5-HT1A, 5HT Receptor, 5HTReceptor, 5-HT7, 5-hydroxytryptamine Receptor, D2, Dopamine, Dopamine Receptor, DopamineReceptor, inhibit, Lurasidone, Inhibitor, SM13496, SM-13496, SM 13496, Serotonin Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.50% (May vary between batches)
Solubility
DMSO:17.83 mg/mL (36.19 mM) ;10% DMSO+90% Corn Oil:1.5 mg/mL (3.04 mM)
Smiles
O=C1[C@H]2[C@@H]3CC[C@@H] (C3) [C@H]2C (=O) N1C[C@@H]1CCCC[C@H]1CN1CCN (CC1) c1nsc2ccccc12
Molecular Formula
C28H36N4O2S
Molecular Weight
492.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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