What sizes are available for FOXP3 (Forkhead Box Protein P3) / Scurfin Mouse Monoclonal Antibody?

FOXP3 (Forkhead Box Protein P3) / Scurfin Mouse Monoclonal Antibody is available in the following size(s): 0.02 mg (With BSA & Azide at 0.2mg/mL), 0.1 mg (With BSA & Azide at 0.2mg/mL), 0.1 mg (Without BSA & Azide at 1mg/mL), 5x 0.1 mg (With BSA & Azide at 0.2mg/mL), 5x 0.1 mg (Without BSA & Azide at 1mg/mL).

FOXP3 (Forkhead Box Protein P3) / Scurfin Mouse Monoclonal Antibody

Q: What is the catalog number for FOXP3 (Forkhead Box Protein P3) / Scurfin Mouse Monoclonal Antibody?

The catalog number for FOXP3 (Forkhead Box Protein P3) / Scurfin Mouse Monoclonal Antibody is MBS438165.

Product Specifications

CAS Number

9007-83-4

Gene Name

[FOXP3]

NCBI Gene ID

50943

Reactivity

Human, Monkey, Mouse

Storage Conditions

Antibody without azide , store at -20°C to -80°C. Non hazardous. No MSDS required.

Specificity

Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.