Maytansine
Maytansine (NSC-153858) is a tubulin-binding ansamycin antibiotic that inhibits microtubule assembly by targeting the rhizoxin site. It is widely used as a research tool in cell biology and oncology for studying mitosis, cytoskeleton dynamics, and in preclinical evaluations of antitumor activity both in vitro and in vivo.
Product Specifications
CAS Number
35846-53-8
Product Name Alternative
Arrest, Antibiotic, Inhibitor, Maitansine, Maitansina, Maytansine, inhibit, NSC153858, NSC-153858, NSC 153858, microtubule-targeted, Microtubule/Tubulin, MicrotubuleAssociated, microtubule, Microtubule Associated, mitotic, subnanomolar, tumor, potent
Field of Research
Infectious Disease & Virology, Signal Transduction
Purity
98.43% (May vary between batches)
Solubility
H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.89 mM) ; DMSO:60 mg/mL (86.68 mM)
Smiles
[H][C@@]12O[C@@]1 (C) [C@H] (CC (=O) N (C) c1cc (C\C (C) =C/C=C\[C@@H] (OC) [C@@]3 (O) C[C@] ([H]) (OC (=O) N3) [C@H]2C) cc (OC) c1Cl) OC (=O) [C@H] (C) N (C) C (C) =O
Molecular Formula
C34H46ClN3O10
Molecular Weight
692.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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