Fluticasone furoate
Fluticasone furoate is a potent synthetic trifluorinated corticosteroid with high glucocorticoid receptor affinity (Kd 0.3 nM) . It is widely used in research models of allergic rhinitis and asthma to study its localized anti-inflammatory effects with minimal systemic exposure in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
397864-44-7
Product Name Alternative
Inhibitor, lipophilic, inhibit, intranasal, fluorinated, Glucocorticoid Receptor, Fluticasone Furoate, Fluticasone furoate, GlucocorticoidReceptor, Allermist, allergic, Anti-inflamatory, anti-asthmatic, Avamys, corticosteroid, CYP3A4, rhinitis, Veramyst
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.58% (May vary between batches)
Solubility
H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.13 mM) ; DMSO:12.5 mg/mL (23.21 mM)
Smiles
[H][C@@]12C[C@@H] (C) [C@] (OC (=O) c3ccco3) (C (=O) SCF) [C@@]1 (C) C[C@H] (O) [C@@]1 (F) [C@@]2 ([H]) C[C@H] (F) C2=CC (=O) C=C[C@]12C
Molecular Formula
C27H29F3O6S
Molecular Weight
538.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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