What is the catalog number for FK-506?

The catalog number for FK-506 is orb1306360.

What sizes are available for FK-506?

FK-506 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does FK-506 come in?

FK-506 is available in 2 different pack sizes.

FK-506 is currently made to order / not held in immediate stock. Contact us for lead time.

FK-506

Tacrolimus is a macrolide immunosuppressant that binds FKBP12, inhibiting calcineurin and subsequent IL-2 production to suppress T-cell activation. It is widely used in research to establish immunosuppression models in vivo and to study T-cell signaling pathways in vitro.

Product Specifications

CAS Number

104987-11-3

Product Name Alternative

Tacrolimus

Field of Research

Immunology & Inflammation

Purity

>98%

Bioactivity

FKBP inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml) .

Smiles

CO[C@@H]1C[C@@H] (CC[C@H]1O) \C=C (/C) [C@H]1OC (=O) [C@@H]2CCCCN2C (=O) C (=O) [C@]2 (O) O[C@@H] ([C@H] (C[C@H]2C) OC) [C@H] (C[C@@H] (C) C\C (C) =C\[C@@H] (CC=C) C (=O) C[C@H] (O) [C@H]1C) OC

Molecular Formula

C44H69NO12

Molecular Weight

804.04

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS) -5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[ (1E) -2-[ (1R,3R,4R) -4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8- (2-propen-1-yl) -15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21 (4H,23H) -tetrone