EGFR

Product Specifications

Gene Name

[EGFR]

NCBI Gene ID

1956

Reactivity

Human. Does not react with mouse and rat.

Storage Conditions

Store at 2 to 8 °C. Antibody is stable for 24 months.

Specificity

This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGFalpha-induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.

Other Gene Names

[EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB; ERBB1; HER1]

Short Name

[EGFR]

Other Product Names

[epidermal growth factor receptor isoform a; Epidermal growth factor receptor; epidermal growth factor receptor; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1]