Temsirolimus
Temsirolimus (CCI-779) is a potent and specific mTOR inhibitor with an IC50 of 1.76 μM. It is clinically used for advanced renal cell carcinoma and is widely applied in oncology research to study mTOR signaling pathways in both cellular and animal models of cancer.
Product Specifications
CAS Number
162635-04-3
Product Name Alternative
CCI-779
Field of Research
Cardiovascular Research
Purity
>98%
Bioactivity
MTOR inhibitor
Form
Powder
Solubility
Ethanol:70 mg/mL (67.94 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:250 mg/mL (242.65 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.94 mM)
Smiles
CO[C@@H]1C[C@H] (C[C@@H] (C) [C@@H]2CC (=O) [C@H] (C) \C=C (C) \[C@@H] (O) [C@@H] (OC) C (=O) [C@H] (C) C[C@H] (C) \C=C\C=C\C=C (C) \[C@H] (C[C@@H]3CC[C@@H] (C) [C@@] (O) (O3) C (=O) C (=O) N3CCCC[C@H]3C (=O) O2) OC) CC[C@H]1OC (=O) C (C) (CO) CO
Molecular Formula
C56H87NO16
Molecular Weight
1030.29
Storage Conditions
-20°C
Notes
For research use only.
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