Fulvestrant
Fulvestrant is a potent estrogen receptor antagonist (IC50=9.4 nM) and a GPR30 agonist. It exhibits antitumor activity by suppressing proliferation and promoting apoptosis and autophagy in breast cancer research, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
129453-61-8
Product Name Alternative
ICI 182780; ZD-9238
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Estrogen receptor antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 50 mg/ml) .
Smiles
[H][C@@]12CC[C@H] (O) [C@@]1 (C) CC[C@]1 ([H]) c3ccc (O) cc3C[C@@H] (CCCCCCCCCS (=O) CCCC (F) (F) C (F) (F) F) [C@@]21[H]
Molecular Formula
C32H47F5O3S
Molecular Weight
606.8
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
7α,17β-[9-[ (4,4,5,5,5-Pentafluoropentyl) sulfinyl]nonyl]estra-1,3,5 (10) -triene-3,17-diol
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