Bax (Apoptosis Marker) Mouse Monoclonal Antibody
Product Specifications
Gene Name
[BAX]
NCBI Gene ID
581
Reactivity
Human, Monkey.<br>Does not react with Mouse and Rat
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Other Gene Names
[BAX; BAX; BCL2L4; BCL2L4; Bcl2-L-4]
Short Name
[Bax]
Other Product Names
[apoptosis regulator BAX isoform 1; Apoptosis regulator BAX; apoptosis regulator BAX; BCL2 associated X, apoptosis regulator; Bcl-2-like protein 4; Bcl2-L-4]
NCBI GI Number
612149787
NCBI Accession Number
NP_001278357.1
NCBI GB Accession Number
NM_001291428.1
Uniprot Accession Number
Q07812
CAS Number
9007-83-4
Available Sizes
Curated Selection
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