Nilotinib monohydrochloride monohydrate
Nilotinib monohydrochloride monohydrate is a potent second-generation BCR-ABL tyrosine kinase inhibitor effective against numerous mutant forms. It is widely used in biochemical and cellular research to study kinase inhibition, resistance mechanisms, and in preclinical models of chronic myeloid leukemia.
Product Specifications
CAS Number
923288-90-8
Product Name Alternative
Tyrosine kinase, inhibit, Nilotinib, Nilotinib (monohydrochloride monohydrate), Nilotinib monohydrochloride, Nilotinib monohydrochloride Monohydrate, Nilotinib monohydrochloride monohydrate, Inhibitor, Autophagy, antitumor, AMN-107, AMN107 (monohydrochloride monohydrate), AMN107 monohydrochloride, AMN107, AMN 107, BcrAbl, Bcr-Abl
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.70% (May vary between batches)
Solubility
DMSO:45 mg/mL (77.06 mM) ;10% DMSO+90% Corn Oil:4 mg/mL (6.85 mM)
Smiles
O.Cl.Cc1cn (cn1) -c1cc (NC (=O) c2ccc (C) c (Nc3nccc (n3) -c3cccnc3) c2) cc (c1) C (F) (F) F
Molecular Formula
C28H22F3N7O.HCl.H2O
Molecular Weight
583.99
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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