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Nilotinib monohydrochloride monohydrate

Nilotinib monohydrochloride monohydrate is a potent second-generation BCR-ABL tyrosine kinase inhibitor effective against numerous mutant forms. It is widely used in biochemical and cellular research to study kinase inhibition, resistance mechanisms, and in preclinical models of chronic myeloid leukemia.

Product Specifications

CAS Number

923288-90-8

Product Name Alternative

Tyrosine kinase, inhibit, Nilotinib, Nilotinib (monohydrochloride monohydrate), Nilotinib monohydrochloride, Nilotinib monohydrochloride Monohydrate, Nilotinib monohydrochloride monohydrate, Inhibitor, Autophagy, antitumor, AMN-107, AMN107 (monohydrochloride monohydrate), AMN107 monohydrochloride, AMN107, AMN 107, BcrAbl, Bcr-Abl

Field of Research

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.70% (May vary between batches)

Solubility

DMSO:45 mg/mL (77.06 mM) ;10% DMSO+90% Corn Oil:4 mg/mL (6.85 mM)

Smiles

O.Cl.Cc1cn (cn1) -c1cc (NC (=O) c2ccc (C) c (Nc3nccc (n3) -c3cccnc3) c2) cc (c1) C (F) (F) F

Molecular Formula

C28H22F3N7O.HCl.H2O

Molecular Weight

583.99

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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