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4-Aminonaphthalimide

4-Amino-1,8-naphthalimide (4-ANI) is a potent small molecule inhibitor of PARP, exhibiting an IC50 value of 180 nM. It is widely used in biochemical research to study DNA repair mechanisms and has been applied in both in vitro assays and in vivo models of cancer and oxidative stress.

Product Specifications

CAS Number

1742-95-6

Product Name Alternative

4 amino 1,8 Naphthalimide, 4-Aminonaphthalimide, 4amino1,8Naphthalimide, 4-amino-1,8-Naphthalimide, Inhibitor, inhibit, PARP, poly ADP ribose polymerase

Field of Research

Epigenetics & Chromatin, Molecular Biology

Purity

>98%

Bioactivity

PARP inhibitor

Form

Powder

Solubility

DMSO:3.6 mg/mL (16.97 mM)

Smiles

Nc1ccc2C (=O) NC (=O) c3cccc1c23

Molecular Formula

C12H8N2O2

Molecular Weight

212.2

Storage Conditions

RT

Notes

For research use only.

Available Sizes

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