TMC647055 Choline Hydroxide Salt
TMC647055 Choline Hydroxide Salt is a potent non-nucleoside HCV NS5B polymerase inhibitor with nanomolar cellular antiviral activity (EC50 = 82 nM) and low cytotoxicity. Its promising preclinical pharmacokinetic profile in animal models supports its ongoing clinical evaluation for hepatitis C virus infection research.
Product Specifications
Product Name Alternative
1204416-97-6, 1204416-97-6 free base, HCVProtease, HCV Protease, HCV NS5B polymerase, TMC647055 Choline Hydroxide Salt, TMC-647055 Choline Hydroxide Salt, TMC647055 Choline Hydroxide Salt (1204416-97-6 free base)
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
99.44% (May vary between batches)
Solubility
DMSO:60 mg/mL (82.43 mM)
Smiles
CN (CCOCCN1C) C (C2=CC3=C (C=CC (OC) =C3) C4=C (C5CCCCC5) C (C=CC (/C (O) =N/S1 (=O) =O) =C6) =C6N4C2) =O.OCC[N+] (C) (C) C.[OH-]
Molecular Formula
C37H53N5O8S
Molecular Weight
727.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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