BCL10 (MALT-Lymphoma Marker) Mouse Monoclonal Antibody
Product Specifications
Gene Name
[BCL10]
NCBI Gene ID
8915
Reactivity
Human
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF-kB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Other Gene Names
[BCL10; BCL10; CLAP; mE10; CIPER; IMD37; c-E10; CARMEN; CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10]
Short Name
[BCL10]
Other Product Names
[B-cell lymphoma/leukemia 10 isoform 1; B-cell lymphoma/leukemia 10; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-containing adapter molecule E10; mE10]
NCBI GI Number
4502379
NCBI Accession Number
NP_003912.1
NCBI GB Accession Number
NM_003921.4
Uniprot Accession Number
O95999
CAS Number
9007-83-4
Available Sizes
Curated Selection
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