PD184161
PD184161 is a potent and orally bioavailable MEK inhibitor with an IC50 in the nanomolar range. It is widely used in cancer research to study the RAS/RAF/MEK/ERK pathway, demonstrating efficacy in both cellular assays and in vivo tumor models.
Product Specifications
CAS Number
212631-67-9
Product Name Alternative
Stroke, cancer, behavioral, Apoptosis, depressive, cell, Mitogen-activated protein kinase kinase, PD184161, PD-184161, PD 184161, neurons, inhibit, Inhibitor, HCC, MAPKK, MAP2K, MEK1/2, MEK
Field of Research
Cell Biology, Signal Transduction
Purity
99.09% (May vary between batches)
Solubility
DMSO:55 mg/mL (98.64 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (4.48 mM)
Smiles
Fc1c (F) c (Nc2ccc (I) cc2Cl) c (cc1Br) C (=O) NOCC1CC1
Molecular Formula
C17H13BrClF2IN2O2
Molecular Weight
557.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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