RN-1 dihydrochloride
RN-1 dihydrochloride is a potent, selective, and irreversible inhibitor of lysine-specific demethylase 1 (LSD1) with an IC50 of 70 nM. This compound is a valuable chemical probe for epigenetic research, enabling the study of LSD1's role in cancer biology and other diseases in both cellular and animal models.
Product Specifications
CAS Number
1781835-13-9
Product Name Alternative
Sickle, RN1, RN-1, RN1 dihydrochloride, RN1 Dihydrochloride, RN-1 Dihydrochloride, RN 1, RN 1 dihydrochloride, RN 1 Dihydrochloride, brain-penetrant, disease, cell, inhibit, irreversible, LSD1, hemoglobin, HbF, Inhibitor, HistoneDemethylase, Histone Demethylase, MAO-B, MAO-A, fetal
Field of Research
Epigenetics & Chromatin, Metabolism Research, Neuroscience
Purity
99.61% (May vary between batches)
Solubility
H2O:18 mg/mL (39.79 mM)
Smiles
Cl.Cl.CN1CCN (CC1) C (=O) CN[C@H]1C[C@@H]1c1ccc (OCc2ccccc2) cc1
Molecular Formula
C23H31Cl2N3O2
Molecular Weight
452.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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