Luminespib
Luminespib (VER-52296) is a potent and selective HSP90 inhibitor targeting both HSP90α and HSP90β isoforms. It demonstrates significant antitumor activity in preclinical studies, including in vitro cell-based assays and in vivo models for head and neck squamous cell carcinoma and other malignancies.
Product Specifications
CAS Number
747412-49-3
Product Name Alternative
NVP-AUY922; VER-52296
Field of Research
Cardiovascular Research, Cell Biology, Immunology & Inflammation
Purity
>99%
Bioactivity
HSP90 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
CCNC (=O) c1noc (c1-c1ccc (CN2CCOCC2) cc1) -c1cc (C (C) C) c (O) cc1O
Molecular Formula
C26H31N3O5
Molecular Weight
465.5
References & Citations
Mohammed Fulayyih Aloufi et al. Luminespib protects against dexamethasone-induced hepatic, vascular, and metabolic abnormalities in rats Naunyn Schmiedebergs Arch Pharmacol, (2025)
Pubmed id
41273382
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5- (2,4-Dihydroxy-5-propan-2-ylphenyl) -N-ethyl-4-[4- (morpholin-4-ylmethyl) phenyl]-1,2-oxazole-3-carboxamide
Available Sizes
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