J-147
J-147 is a synthetic curcumin derivative developed as a neuroprotective and neurogenic research compound. It has shown efficacy in preclinical models of aging, Alzheimer's disease, and diabetic neuropathy, impacting multiple relevant pathways. Studies include both in vitro assays and in vivo experiments using accelerated aging mouse models.
Product Specifications
CAS Number
1146963-51-0
Product Name Alternative
SLC6A3, oxidase, transporte, Alzheimer, barrier, BBB, BDNF, brain, blood, disease, dopamine, DopamineReceptor, Dopamine Transporter, Dopamine Receptor, DAT, inhibit, J147, J-147, J 147, MonoamineOxidase, Monoamine Oxidase, monoamine, neuroprotective, MAO, MAO B, Inhibitor, Epigenetic Reader Domain, EpigeneticReaderDomain
Field of Research
Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery
Purity
99.30% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.85 mM) ; DMSO:45 mg/mL (128.45 mM)
Smiles
COc1cccc (\C=N\N (C (=O) C (F) (F) F) c2ccc (C) cc2C) c1
Molecular Formula
C18H17F3N2O2
Molecular Weight
350.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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