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J-147

J-147 is a synthetic curcumin derivative developed as a neuroprotective and neurogenic research compound. It has shown efficacy in preclinical models of aging, Alzheimer's disease, and diabetic neuropathy, impacting multiple relevant pathways. Studies include both in vitro assays and in vivo experiments using accelerated aging mouse models.

Product Specifications

CAS Number

1146963-51-0

Product Name Alternative

SLC6A3, oxidase, transporte, Alzheimer, barrier, BBB, BDNF, brain, blood, disease, dopamine, DopamineReceptor, Dopamine Transporter, Dopamine Receptor, DAT, inhibit, J147, J-147, J 147, MonoamineOxidase, Monoamine Oxidase, monoamine, neuroprotective, MAO, MAO B, Inhibitor, Epigenetic Reader Domain, EpigeneticReaderDomain

Field of Research

Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery

Purity

99.30% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.85 mM) ; DMSO:45 mg/mL (128.45 mM)

Smiles

COc1cccc (\C=N\N (C (=O) C (F) (F) F) c2ccc (C) cc2C) c1

Molecular Formula

C18H17F3N2O2

Molecular Weight

350.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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