GDC-0941
Pictilisib (GDC-0941) is a potent, pan-class I PI3K inhibitor with IC50 values of 3, 33, 3, and 75 nM against p110α, β, δ, and γ isoforms, respectively. It is widely used in preclinical cancer research, demonstrating antitumor activity in both cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
957054-30-7
Product Name Alternative
GNE-0941; Pictilisib
Field of Research
Cancer Biology
Purity
>98%
Bioactivity
Pan-PI3K inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 60 mg/ml) .
Smiles
CS (=O) (=O) N1CCN (Cc2cc3nc (nc (N4CCOCC4) c3s2) -c2cccc3[nH]ncc23) CC1
Molecular Formula
C23H27N7O3S2
Molecular Weight
513.6
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2- (1H-Indazol-4-yl) -6-[[4- (methylsulfonyl) -1-piperazinyl]methyl]-4- (4-morpholinyl) -thieno[3,2- d]pyrimidine
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