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JNJ-31020028

JNJ-31020028 is a potent, brain-penetrant, and selective neuropeptide Y2 receptor antagonist. It demonstrates high affinity for human and rat Y2 receptors with over 100-fold selectivity versus Y1, Y4, and Y5 subtypes. This compound is a valuable research tool for investigating Y2 receptor function in both in vitro assays and in vivo models of anxiety, depression, and feeding behavior.

Product Specifications

CAS Number

1094873-14-9

Product Name Alternative

Inhibit, norepinephrine, NPY receptor, JNJ 31020028, JNJ31020028, JNJ-31020028, microdialysis, Neuropeptide Y Receptor, neuropeptide Y2 receptor, neuropeptide Y (NPY) receptor, NeuropeptideYReceptor, hypothalamus, Inhibitor, anxiety, depression, stress-induced anorexia

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

95.92% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.77 mM) ; DMSO:5.66 mg/mL (10.01 mM)

Smiles

CCN (CC) C (=O) C (N1CCN (CC1) c1ccc (NC (=O) c2ccccc2-c2cccnc2) cc1F) c1ccccc1

Molecular Formula

C34H36FN5O2

Molecular Weight

565.68

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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