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CHS-828 (GMX-1778)

CHS-828 (GMX1778) is a potent small molecule NAMPT inhibitor with an IC50 below 25 nM, disrupting cellular NAD+ biosynthesis. It is a valuable research tool for studying cancer metabolism and has demonstrated antitumor efficacy in both cellular assays and in vivo xenograft models.

Product Specifications

CAS Number

200484-11-3

Product Name Alternative

GMX-1778

Field of Research

Cell Biology, Epigenetics & Chromatin, Stem Cell & Developmental Biology

Purity

>98%

Bioactivity

NAMPT inhibitor

Form

Powder

Solubility

Soluble in DMSO up to 25 mg/ml)

Smiles

Clc1ccc (OCCCCCCNC (NC#N) =Nc2ccncc2) cc1

Molecular Formula

C19H22ClN5O

Molecular Weight

371.86

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

N-[6- (4-chlorophenoxy) hexyl]-N'-cyano-N''-4-pyridinyl-guanidine

Available Sizes

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